Category Archives: Chapter 5 Cancer Tables isolates

Ascites Carcinoma

April 1, 2014 brian

Malignant ascites indicates the presence of malignant cells in the peritoneal cavity and is a grave prognostic sign. While survival in this patient population is poor, averaging about 20 weeks from time of diagnosis, quality of life can be improved through palliative procedures.

Source

Sangisetty, S., & Miner, T.J. Malignant ascites: A review of prognostic factors, pathophysiology and therapeutic measures. World J Gastrointest Surg. 2012 April 27; 4(4): 87–95. doi:10.4240/wjgs.v4.i4.87

Ascites Carcinoma
Cell Type	Herb Source(s)	Isolate	Refs
Ehrlich	Hippophae rhamnoides	Isorhamnetin	Zhu et al., 2005
Ehrlich	Rabdosia rubescens	Oridonin	Zhou et al., 2007

Chapter 5 Cancer Tables isolates

Multi-Drug Resistance

Multi-drug Resistance
Cell Type	Herb Source(s)	Isolate	Refs
Multi-drug resistance in breast carcinoma	derived from the greater celandine	Chelerythrine	Zhe et al., 2011
Multi-drug resistance	derived from the greater celandine	Chelidonine	Nadova et al., 2008
Multi-drug resistance	derived from the greater celandine	Chelidonine	El-Readi, Eid, Ashour, Tahrani, & Wink, 2013
Multi-drug resistance		Cnidiadin	Barthomeuf et al., 2005
Multi-drug resistance	Rheum palmatum., Senna obtusifolia, Fallopia japonica, Kalimeris indica, Ventilago madraspatana, Rumex nepalensis, Fallopia multiflora, Cassia occidentalis, Senna siamea, Acalypha australis	Emodin	Jiang et al., 2009
Multi-drug resistance	Panax genus	Ginsenosides	Yun et al., 2013
Multi-drug resistance	Panax genus	Ginsenosides	Kwon et al., 2008
Multi-drug resistance	Rubia cordifolia	Mollugin	Tran et al., 2013
Multi-drug resistance	Scutellaria barbata	Pheoborbide	Cheung et al., 2013
Multi-drug resistance	fruits, vegetables, leaves, grains, red wine	Quercetin	Kothan et al., 2004
Multi-drug resistance		Schisandrin B	Sun, Xu, Lu, Pan, & Hu, 2007
Multi-drug resistance	various fruits, vegetables	Biochanin	Chung et al., 2005
Multi-drug resistance	Panax genus	Ginsenosides	Jia et al., 2004
Multi-drug-sensitive and -resistant	Salvinal	Salvia miltiorrhizae	Chang et al., 2004
Multi-drug	Radix Angelica sinensis	Coniferyl Ferulate	Chen et al., 2013
Multi-drug	Curcuma longa	Curcumin	Chang et al., 2006
Multi-drug	Magnolia genus	Honokiol	Xu et al., 2006
Multi-drug	Lithospermum erythrorhizon	Shikonin	Wiench et al., 2012
tumors in various target organs	fruits and vegetables, particularly green tea Camellia sinensis	Green Tea 95% Polyphenols	Khan et al., 1992
tumors drug-resistant	Saussurea lappa	Dehydrocostus lactone	Kretschmer et al., 2013
various cancer	Scutellaria radix, Scutellaria rivularis, Scutellaria baicalensis, Scutellaria lateriflora	Baicalein	Li, 2008
various cancers	Andrographis paniculata	Andrographolide	Zhou, 2008
cancer advanced or metastatic	various Garcinia species	Gambogic acid	Chi et al., 2013
cancer apoptosis	Rabdosia rubescens	Oridonin	Fujita et al., 1970; Fujita et al., 1976; Henan Medical Institute, 1978; Fujita et al., 1988; Fujita 1988
cancer cell death	Tanacetum parthenium	Parthenolide	Koprowska et al., 2010
cancer chemo-preventive	fruits and vegetables, particularly green tea Camellia sinensis	Green Tea 95% Polyphenols	Ahmad et al., 1999
canine cancer Non specific	derivative of artemisinin	Artesunate	Rutteman, 2013

Chapter 5 Cancer Tables isolates

Uterine Cancer (See Endometrial Cancer)

The terms uterine cancer may refer to any of several different types of cancer which occur in the uterus, namely:

Uterine sarcomas: sarcomas of the myometrium, or muscular layer of the uterus, are most commonly leiomyosarcomas.

Endometrial cancer:

• Endometrial carcinomas originate from cells in the glands of the endometrium (uterine lining). These include the common and readily treatable well-differentiated endometrioid adenocarcinoma, as well as the more aggressive uterine papillary serous carcinoma and uterine clear-cell carcinoma.

• Endometrial stromal sarcomas originate from the connective tissues of the endometrium, and are far less common than endometrial carcinomas.

• Malignant mixed Müllerian tumors are rare endometrial tumors which show both glandular (carcinomatous) and stromal (sarcomatous) differentiation – carcinosarcoma behaves similar to a high grade carcinoma, and it is felt to be of epithelial origin rather than true sarcoma.

Source

Cancer Research UK (2103) http://www.cancerresearchuk.org/cancer-help/type/womb-cancer/

Uterine Cancer
Cell Type	Herb Source(s)	Isolate	Refs
Multi-drug-resistant	Magnolia genus	Honokiol	Angelini et al., 2010

Chapter 5 Cancer Tables isolates

Neurological cancers

Neurological cancers
Category	Herb Source(s)	Isolate	Refs
Non specific	Curcuma longa	Curcumin	Anand et al., 2008

Chapter 5 Cancer Tables isolates

Choriocarcinoma

Choriocarcinoma is a malignant, trophoblastic cancer, usually of the placenta. It is characterized by early hematogenous spread to the lungs. It belongs to the malignant end of the spectrum in gestational trophoblastic disease (GTD). It is also classified as a germ cell tumor and may arise in the testis or ovary.

Source

Dorland’s Medical Dictionary http://web.archive.org/web/20090628165559/http://www.mercksource.com/pp/us/cns/cns_hl_dorlands_split.jsp?pg=/ppdocs/us/common/dorlands/dorland/two/000020875.htm

Choriocarcinoma
Cell Type	Herb Source(s)	Isolate	Refs
Non specific	Trichosanthes kirilowii	Trichosanthin	Sha et al., 2013

Chapter 5 Cancer Tables isolates, Colon Cancer or Colorectal cancer

Rectal Cancer (See Colorectal Cancer)

Colorectal cancer, also known as colon cancer, rectal cancer, or bowel cancer, is a cancer from uncontrolled cell growth in the colon or rectum.

Rectal Cancer
Cell Type	Herb Source(s)	Isolate	Refs
Non specific	Sophora Flavescens	Matrine	Yin et al., 2013

Chapter 5 Cancer Tables isolates

Skin Cancer

Skin cancers are named after the type of skin cell from which they arise. Basal cell cancer originates from the lowest layer of the epidermis, and is the most common but least dangerous skin cancer. Squamous cell cancer originates from the middle layer, and is less common but more likely to spread and, if untreated, become fatal. Melanoma, which originates in the pigment-producing cells (melanocytes), is the least common, but most aggressive.

Basal cell carcinoma

Basal cell carcinoma usually presents as a raised, smooth, pearly bump on the sun-exposed skin of the head, neck or shoulders. Sometimes small blood vessels can be seen within the tumor. Crusting and bleeding in the center of the tumor frequently develops. It is often mistaken for a sore that does not heal. This form of skin cancer is the least deadly and with proper treatment can be completely eliminated, often without scarring.